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Mirena (levonorgestrel-releasing intrauterine device) is a progestin-containing intrauterine system (IUS, also called an intrauterine device, or IUD) indicated for: Prevention of pregnancy for up to 7 years Treatment of heavy menstrual bleeding for women who choose to use Intrauterine contraception as their method of contraception for up to 5 years Common side effects of Mirena include: Missed periods (amenorrhea) Bleeding and spotting between periods Heavier bleeding during the first few weeks after device insertion Abdominal/pelvic pain Vaginal discharge Inflammation or irritation of the vagina/vulva Ovarian cysts Back pain Headache Migraine Nervousness Dizziness Nausea Vomiting Bloating Breast tenderness or pain Weight gain Changes in hair growth Acne Depression Mood changes Loss of interest in sex Itching Skin rash Puffiness in the face, hands, ankles, or feet Possible serious side effects of Mirena include: Risk of ectopic pregnancy, which is when a pregnancy occurs outside the uterus Severe infection or sepsis (which may be life-threatening), including Group A streptococcal sepsis (GAS) Pelvic inflammatory disease (PID) Perforation (total or partial, including penetration/embedment of Mirena in the uterine wall or cervix) Partial or complete expulsion of Mirena Ovarian cysts If left in place during pregnancy: Severe infection Miscarriage Premature birth Death of the mother Who Should Not Use Mirena
